Month: September 2024

Metsera’s-Long-Acting-GLP-1

Metsera’s Long-Acting GLP-1; Mount Sinai Partners with Noom; Wegovy and Medicare Price Negotiations; New Guidelines for Bariatric Surgery; WeightWatchers CEO is Out.

AT A GLANCE STAT’s Elaine Chen on Novo Nordisk’s trial of cannabinoid CB1 receptor inhibitor monlunabant, with modest 6.4% weight loss and some psychiatric side effects. Metsera announced phase 1 clinical trial results of MET-097, a long-acting injectable GLP-1 drug with weight reduction of 7.5% at day 36. Modern Healthcare on Mount Sinai partnering with Noom, aimed at behavioral approaches to weight loss. Medicare spent $5.6B on

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Bernie Sanders on GLP-1 Pricing; Hims &Hers Offers Compounded GLP-1s for $99/Month; Cannabis-Based Weight Loss Meds.

AT A GLANCE On x.com Senator Bernie Sanders said once Ozempic’s exclusivity ends, drug manufacturers could sell generic versions for less than $100 per month. Dr. Daniela Lamas writes on GLP-1 meds in The New York Times, that the drugs’ ‘…numerous benefits are pointing to an emerging cause of so much human disease: inflammation.’ Dr. Lotte Bjerre Knudsen at Novo Nordisk, who led the team that

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Obesity-Rates-Are-Rising-Across-the-US

Obesity Rates Are Rising Across the US; Novo, Roche and Other Report New Weight Loss Data; NOOM offers Compounded GLP-1s; Kim Kardashian Launches Plant-Based Ozempic-Style Substance.

AT A GLANCE Terns Pharmaceuticals released data that 67% of patients taking the highest dose of TERN-601 lost at least 5% of their body weight at 28 days. STAT on Novo Nordisk reported that its new obesity pill that targets the amylin hormone led to substantial weight loss in an early study. Trust for America’s Health on obesity rates for U.S. adults were at or higher than 35

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Wegovy’s-the-Word;-Preserving-Muscle-Mass

Wegovy’s the Word; Preserving Muscle Mass: BioAge Labs Files for IPO; Amylin Hots Up in Combination with GLP-1 Meds; 20% of US Adults with Diabetes Taking GLP-1 Drugs.

AT A GLANCE Andrew Joseph at STAT writes from the European Society of Cardiology’s annual meeting in London, that ‘…Wegovy’s the word.’ The Peterson-KFF Health System Tracker writes ‘…over 40% of adults under 65 with private insurance could be indicated for a GLP-1 drug…’ totaling 57.4 million US adults. Quartz reports on BioAge Labs leading drug candidate azelaprag, a pill that mimics apelin, when taken with a

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DEXCOM’s CGM for Consumers; Biden Slams GLP-1 Pricing; Eli Lilly Launches Single-Dose Vials; Hims&Hers Stock Plummets; Semaglutide Lowers COVID-19 Death Rate by 34%.

AT A GLANCE STAT notes ‘…Glucose tracking is the future, Dexcom executives gushed at a glitzy launch event…’ A busy week on GLP-1 pricing… first, with NBC News referring to Novo Nordisk CEO Lars Fruergaard Jorgensen defending the high cost of Ozempic and Wegovy in the U.S. Eli Lilly unexpectedly ‘…announced Zepbound 2.5 mg and 5 mg single-dose vials are available… at a 50% or greater

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