Category: GLP-1 therapy

Novo-Asks-FDA-to-Restrict-Compounded-GLP-1-Meds

Novo Asks FDA to Restrict Compounded GLP-1 Meds; The Economist’s Ozempic Edition; GLP-1 May Drive Lower Rates of Opioid and Alcohol Use, and Alzheimer’s Disease.

AT A GLANCE Novo Nordisk wants to prevent compounding pharmacies from making its GLP-1 meds, as they are too complex for manufacturers to make safely, per CNBC. Elaine Chen, Lizzy Lawrence and Ed Silverman at STAT on the FDA’s current flat-spin, on its about-face on shortages of Eli Lilly drug tirzetapide. My favorite weekly news read, The Economist, leads with ‘The everything drugs’ in the

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Bernie Sanders on GLP-1 Pricing; Hims &Hers Offers Compounded GLP-1s for $99/Month; Cannabis-Based Weight Loss Meds.

AT A GLANCE On x.com Senator Bernie Sanders said once Ozempic’s exclusivity ends, drug manufacturers could sell generic versions for less than $100 per month. Dr. Daniela Lamas writes on GLP-1 meds in The New York Times, that the drugs’ ‘…numerous benefits are pointing to an emerging cause of so much human disease: inflammation.’ Dr. Lotte Bjerre Knudsen at Novo Nordisk, who led the team that

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Wegovy’s-the-Word;-Preserving-Muscle-Mass

Wegovy’s the Word; Preserving Muscle Mass: BioAge Labs Files for IPO; Amylin Hots Up in Combination with GLP-1 Meds; 20% of US Adults with Diabetes Taking GLP-1 Drugs.

AT A GLANCE Andrew Joseph at STAT writes from the European Society of Cardiology’s annual meeting in London, that ‘…Wegovy’s the word.’ The Peterson-KFF Health System Tracker writes ‘…over 40% of adults under 65 with private insurance could be indicated for a GLP-1 drug…’ totaling 57.4 million US adults. Quartz reports on BioAge Labs leading drug candidate azelaprag, a pill that mimics apelin, when taken with a

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DEXCOM’s CGM for Consumers; Biden Slams GLP-1 Pricing; Eli Lilly Launches Single-Dose Vials; Hims&Hers Stock Plummets; Semaglutide Lowers COVID-19 Death Rate by 34%.

AT A GLANCE STAT notes ‘…Glucose tracking is the future, Dexcom executives gushed at a glitzy launch event…’ A busy week on GLP-1 pricing… first, with NBC News referring to Novo Nordisk CEO Lars Fruergaard Jorgensen defending the high cost of Ozempic and Wegovy in the U.S. Eli Lilly unexpectedly ‘…announced Zepbound 2.5 mg and 5 mg single-dose vials are available… at a 50% or greater

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Eli-Lilly-Boosted-&-Novo-Nordisk-Down

Eli Lilly Boosted & Novo Nordisk Down; The Wild West of Online GLP-1 Sites; Bowling Green, KY aka ‘Ozempictown’; Hims Doubles Down on Compounded GLP-1s

AT A GLANCE Forget Ozempic says Business Insider – an under-the-radar antiaging supplement is the next hot commodity in Hollywood. STAT notes Eli Lilly boosts 2024 revenue guidance by $3 billion, driven by massive sales of Mounjaro and Zepbound. STAT reports an underwhelming earnings report and ongoing questions about increasing competition that sent Novo Nordisk’s shares down. Dr. Scott Kahan says in STAT of online prescribers ‘…The world of obesity and

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UK-Approves-Wegovy-for-Heart-Risks

UK Approves Wegovy for Heart Risks; Viking Therapeutics and Roche on the Obesity Meds Charge; Up to 2 Million Americans on Compounded GLP-1s.

AT A GLANCE Reuters writes Novo Nordisk’s Wegovy gets UK approval for use to lower heart risks. Viking Therapeutics will move VK2735, its injectable GLP-1/GIP obesity drug, directly into a Phase 3 trial, as per Elain Chen at STAT. STAT notes Roche CEO Thomas Schinecker’s comment on weight loss drugs, ‘…It’s going to be a huge market.’ CBS News reports ‘…several large compounding pharmacies are provisioning up

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Biden & Saunders on GLP-1 Prices

Biden & Saunders on GLP-1 Prices; Foodsmart on Telehealth Nutrition; Ozempic and Food Noise; GLP-1s and Eye Stroke; Cancer Risks Decrease with GLP-1 Meds.

AT A GLANCE President Biden and Senator Sanders write in USA Today that ‘…Novo Nordisk, Eli Lilly must stop ripping off Americans with high drug prices.’ Foodsmart founder and CEO Dr. Jason Langheier is profiled by Forbes, with his company as ‘…the largest foodcare provider in the United States.’ Lauren J. Young at Scientific American wants to understand how ‘Ozempic Quiets Food Noise in the Brain.’ Not

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USPTF on Kids with Obesity_ GLP-1s on Brain Diseases_ Financial Incentives to Lose Weight_ Novel Amylin Drug Drives 8.6% Weight Loss at 16 Weeks

USPTF on Kids with Obesity; GLP-1s on Brain Diseases; Financial Incentives to Lose Weight; Novel Amylin Drug Drives 8.6% Weight Loss at 16 Weeks

AT A GLANCE The US Preventive Services Task Force published in JAMA a Recommendation Statement on Interventions for High Body Mass Index in Children and Adolescents. Simar Bajaj at NewScientist on GLP-1s’ unexpected effects on the brain, to treat depression, anxiety, addiction and Alzheimer’s. JAMA Pediatrics publishes the impact of financial incentives on improved outcomes of a dietary intervention among 126 adolescents with severe obesity. Zealand Pharma drug petrelintide, which targets the

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MASH-Clash-for-Liver-Disease;-Google’s-Verily-Pivots-to-GLP-1-Meds;-JPMorgan-Chase-$500M-Bet-on-Weight-Loss-Meds;-MIT’s-Bob-Langer-Launches-NewCo;-40%-Increase-in-Type-2-Diabetes-in-Young-People

MASH Clash for Liver Disease; Google’s Verily Pivots to GLP-1 Meds; JPMorgan Chase $500M Bet on Weight-Loss Meds; MIT’s Bob Langer Launches NewCo; 40% Increase in Type 2 Diabetes in Young People

AT A GLANCE STAT on Google’s health tech spinout Verily pivoting to offer GLP-1 drug prescriptions. MIT biotech legend Bob Langer and colleague Giovanni Traverso launched Syntis Bio, with a technology to coat the stomach, that impacts obesity. From Yahoo! Finance, JPMorgan Chase & Co.’s asset-management arm raised a  $500 million fund to invest in weight-loss drugs. From Reuters, roughly one-third of US employer health plans are covering

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Oral GLP-1 Charge; Weight Loss Drugs and Cancer; The Obese Police; Medicaid Coverage for Comprehensive Obesity Care.

Oral GLP-1 Charge; Weight Loss Drugs and Cancer; The Obese Police; Medicaid Coverage for Comprehensive Obesity Care.

AT A GLANCE Structure Therapeutics announced weight loss of 6.2% at 12 weeks in 37 subjects on GSBR-1290 – a once-daily oral GLP-1 drug. UK-based The Guardian newspaper reports ‘…Weight-loss drugs offer a new weapon in the global fight against cancer…’ STAT notes Eli Lilly’s Zepbound obesity drug ‘…improved living scarring in a mid-stage study of the liver disease MASH.’ Tamar Haspel at The Atlantic refers to new guidelines

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