Category: Obesity Treatment

FDA Sued on Removal of Tirzetapide from Shortage List; Eli Lilly Sends Cease-and-Desist Letters; Could we have Hit Peak Obesity?

AT A GLANCE STAT reports The Outsourcing Facilities Association, has sued the FDA for a ‘reckless and arbitrary’ decision to remove tirzetapide from the shortages list. Eli Lilly is sending hundreds of cease-and-desist letters to telehealth companies, compounding pharmacies and medical spas, from Bloomberg. Christina Farr at Second Opinion asks Could we have hit “peak obesity” The Congressional Budget Office reports on the estimated budgetary effects of an illustrative policy to

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Roche,-Metsera-and-Kailera-Advance-on

Roche, Metsera and Kailera Advance on Obesity Drug Development; Tirzetapide Shortage is Over, per FDA; and, Obesity-First Care.

AT A GLANCE From STAT, Chief Executive of Roche’s pharma division, Teresa Graham, says on weight loss drugs ‘… that in a $100- to $250-billion market, there’s a lot of room for multiple players.’ Obesity start-up Metsera ‘…is partnering with drug manufacturer Amneal Pharmaceuticals…’ as per Elaine Chen at STAT. STAT reports Atlas Venture and Bain Capital Life Sciences are launching a new startup with $400 million

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Obesity-Rates-Are-Rising-Across-the-US

Obesity Rates Are Rising Across the US; Novo, Roche and Other Report New Weight Loss Data; NOOM offers Compounded GLP-1s; Kim Kardashian Launches Plant-Based Ozempic-Style Substance.

AT A GLANCE Terns Pharmaceuticals released data that 67% of patients taking the highest dose of TERN-601 lost at least 5% of their body weight at 28 days. STAT on Novo Nordisk reported that its new obesity pill that targets the amylin hormone led to substantial weight loss in an early study. Trust for America’s Health on obesity rates for U.S. adults were at or higher than 35

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Eli Lilly Report 94% Reduction in Diabetes Risk on Tirzetapide; Employers Budgeting 7.8% Increase in Healthcare Costs; From the UK, ‘Lose Weight, or Lose Your Healthcare!’

AT A GLANCE Eli Lilly reports tirzetapide ‘…reduced the risk of developing type 2 diabetes by 94% in adults with pre-diabetes and obesity or overweight.’ Modern Healthcare reports that ‘…employers budgeting for a 7.8% increase in healthcare costs in 2025. Lose the weight, or lose state-funded healthcare, says The Telegraph newspaper from the UK. JAMA Network Open publishes a review of World Health Organization data, of 107 suicidal

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UK-Approves-Wegovy-for-Heart-Risks

UK Approves Wegovy for Heart Risks; Viking Therapeutics and Roche on the Obesity Meds Charge; Up to 2 Million Americans on Compounded GLP-1s.

AT A GLANCE Reuters writes Novo Nordisk’s Wegovy gets UK approval for use to lower heart risks. Viking Therapeutics will move VK2735, its injectable GLP-1/GIP obesity drug, directly into a Phase 3 trial, as per Elain Chen at STAT. STAT notes Roche CEO Thomas Schinecker’s comment on weight loss drugs, ‘…It’s going to be a huge market.’ CBS News reports ‘…several large compounding pharmacies are provisioning up

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Englands’-NHS-not-Taking-Obesity-Seriously

Englands’ NHS not Taking Obesity Seriously; Pfizer, Vivani Medical and Rani Therapeutics Chase Novo/Lilly Duopoly; Ozempic Cuts Dementia Risk by Half; Tirzetapide 3 x Effective as Semaglutide

AT A GLANCE The Guardian newspaper reports ‘…Much of the NHS does not take obesity seriously enough.’ Reuters on only ‘…one in four U.S. patients prescribed Novo Nordisk’s Wegovy or Ozempic for weight loss were still taking the popular medications two years later.’ Vivani Medical plans to launch an investigational six-month program for its GLP-1 implant NPM-115. Rani Therapeutics, announces commercialization of RT-114, an oral

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USPTF on Kids with Obesity_ GLP-1s on Brain Diseases_ Financial Incentives to Lose Weight_ Novel Amylin Drug Drives 8.6% Weight Loss at 16 Weeks

USPTF on Kids with Obesity; GLP-1s on Brain Diseases; Financial Incentives to Lose Weight; Novel Amylin Drug Drives 8.6% Weight Loss at 16 Weeks

AT A GLANCE The US Preventive Services Task Force published in JAMA a Recommendation Statement on Interventions for High Body Mass Index in Children and Adolescents. Simar Bajaj at NewScientist on GLP-1s’ unexpected effects on the brain, to treat depression, anxiety, addiction and Alzheimer’s. JAMA Pediatrics publishes the impact of financial incentives on improved outcomes of a dietary intervention among 126 adolescents with severe obesity. Zealand Pharma drug petrelintide, which targets the

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Novo’s Semaglutide for Heart Failure; Biocon Leads India’s Generic GLP-1 Charge; I’m a Doctor on Ozempic; Cost-Effectiveness of Semaglutide Versus Endoscopic Sleeve

Novo’s Semaglutide for Heart Failure; Biocon Leads India’s Generic GLP-1 Charge; I’m a Doctor on Ozempic; Cost-Effectiveness of Semaglutide Versus Endoscopic Sleeve

AT A GLANCE Biocon Ltd. is leading India’s push to weight loss medications as patents lapse, unleashing generic supply for the global weight-loss market, from Bloomberg. STAT News reports European regulators ‘…have found no evidence that GLP-1 drugs like Ozempic and Wegovy cause suicidal thoughts or actions.’ ‘I’m a doctor on Ozempic – it’s effective under one condition…’ says President and CEO of Philadelphia College of Osteopathic Medicine,

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Anti-Obesity Meds for those with HIV; Medicare Approval Likely for Wegovy; Amazon Delivery of GLP-1 Meds; Obesity Treatment in Primary Care

Anti-Obesity Meds for those with HIV; Medicare Approval Likely for Wegovy; Amazon Delivery of GLP-1 Meds; Obesity Treatment in Primary Care

AT A GLANCE Nature journal reports ‘…People with HIV are the latest group to benefit from the new generation of anti-obesity drugs.’ STAT suggests FDA approval of Wegovy for heart benefits ‘…could provide a backdoor way to expand access to the drug for people on Medicare.’ Peter Loftus at The Wall Street Journal reveals those ‘…seeking a popular new weight-loss drug will have a new home-delivery option from

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GLP-1 for Kidney Disease; FDA approves Wegovy for Cardiovascular Disease; Eli Lilly’s new Ad Campaign ahead of the Oscars; Obesity is South Africa’s New HIV Epidemic.

GLP-1 for Kidney Disease; FDA approves Wegovy for Cardiovascular Disease; Eli Lilly’s new Ad Campaign ahead of the Oscars; Obesity is South Africa’s New HIV Epidemic.

AT A GLANCE Novo Nordisk’s FLOW trial of Ozempic demonstrates a ‘…24% reduction in the risk of kidney disease-related events…’ STAT reports on Novo Nordisk’s phase 1 trial of experimental oral medicine amycretin, with an average of 13.1% weight loss after 12 weeks. Reuters informs on Novo Nordisk market cap of $556 billion and had surpassed that of Tesla. The FDA approved ‘…a new indication for use

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